The basic cause of acne is still unknown. It seems to be a multifactorial disease in which interaction of several factors play an important part in the pathogenesis. The primary event may be (a) obstruction of the sebaceous duct due to alteration in the pattern of keratinization within the follicle, (b) abnormal sebum production with excess quantities or altered composition or (c) increased bacterial colonization (proprionibacterium acnes and staphylococcus epidermi¬dis of pilosebaceous follicles which furnish the lipases responsible for hydrolysis of sebum triglycerides into free fatty acids. All three mechanisms may be involved. Obstruction of duct leads to forma¬tion of a comedone, the initial lesion of acne. A comedone can be located either in a closed follicle as a 'white head' consisting of lipid and keratin, or in an open follicle as 'black head' consisting of keratin and lipid with melanin deposition. The continual accumula¬tion of keratin and lipid may lead to rupture of the follicular wall and release of its contents into the surrounding dermis provoking an inflammatory tissue reaction.
This better acne therapy merges environment as well as medication to produce a really exclusive and effectual medicine. The Tea tree oil works like an antiseptic and anti-stirring instrument when the benzoyl lighten gets to act demolishing spots and struggling off new eruptions. The mixture of these 2 very efficient constituents made for a medicine, which transports theatrical output in some days. Can be freshening at the start, it's significant that you go behind the orders on the tag to make sure that your body doesn't befall annoyed.
2. Clean your face at least two to three times each day. Keep it clean.
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